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<h3>Overview</h3>
<p><strong>Abemaciclib</strong> is a selective CDK4/6 inhibitor synthesized via advanced organic coupling. Molecular formula: C<sub>27</sub>H<sub>29</sub>N<sub>7</sub>O<sub>3</sub>; CAS No.: 1231929-97-5.</p>
<h3>Application</h3>
<ul>
<li>Targeted therapy for hormone receptor-positive, HER2-negative breast cancer.</li>
<li>Combination with endocrine therapy in metastatic or locally advanced settings.</li>
<li>Clinical trials exploring efficacy in other solid tumors with CDK4/6 dysregulation.</li>
</ul>
<h3>Precautions</h3>
<p>Monitor for diarrhea and neutropenia. Store below 25°C in dry, sealed containers away from light. Use only under strict medical supervision.</p>