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Other Specialized Reagents

99% up 8-Chloro-5,10-Dihydrodibenzo[B,E][1,4]Diazepin-11-One Clozapine Intermediate 50892-62-1

Category:

Other Specialized Reagents

CAS NO:

50892-62-1

Standard:

USP,BP,EP,JP,In-house Standards,

Price Range:

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Sinoway Industrial Co. Ltd

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Basic Info

CAS Number

50892-62-1

Pharmacopoeia

USP,BP,EP,JP,In-house Standards

Grade

Pharmaceutical Grade

Is Manufacturer

YES

Packaging & Delivery

Packaging Specification

1kg/bottle

Delivery Cycle

7 days after payment

Product Description

Product Information

Product name	8-Chloro-5,10-dihydrodibenzo[b,e][1,4]diazepin-11-one Clozapine intermediate
CAS No.	50892-62-1
Molecular Formula	C13H9ClN2O
Molecular Weight	244.68
Quality Standard	99% up by HPLC, GMP
Appearance	White powder

Molecular Structure

Synonyms

8-Chloro-5H-dibenzo[b,e][1,4]diazepin-11(10H)-one

Specification

The systematic name of 8-Chloro-5,10-dihydrodibenzo[b,e][1,4]diazepin-11-one is 8-chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one. With the CAS registry number 50892-62-1, it is also named as 11H-dibenzo[b,e][1,4]diazepin-11-one, 8-chloro-5,10-dihydro-. The product's categories are (Intermediate of Clozapine); Aromatics Compounds; Aromatics; Intermediates & Fine Chemicals; Pharmaceuticals. It is white solid which is a useful intermediate for the preparation of pharmaceutical actives and fine chemicals.

The other characteristics of 8-Chloro-5,10-dihydrodibenzo[b,e][1,4]diazepin-11-one can be summarized as: (1)ACD/LogP: 3.34; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 3.34; (4)ACD/LogD (pH 7.4): 3.34; (5)ACD/BCF (pH 5.5): 201.98; (6)ACD/BCF (pH 7.4): 201.97; (7)ACD/KOC (pH 5.5): 1555.07; (8)ACD/KOC (pH 7.4): 1554.99; (9)#H bond acceptors: 3; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 0; (12)Index of Refraction: 1.629; (13)Molar Refractivity: 65.51 cm3; (14)Molar Volume: 184.3 cm3; (15)Polarizability: 25.97×10-24 cm3; (16)Surface Tension: 47.2 dyne/cm; (17)Density: 1.327 g/cm3; (18)Flash Point: 156 °C; (19)Enthalpy of Vaporization: 57.74 kJ/mol; (20)Boiling Point: 334.4 °C at 760 mmHg; (21)Vapour Pressure: 0.000128 mmHg at 25°C.

People can use the following data to convert to the molecule structure.
1. SMILES:Clc3cc2NC(=O)c1c(cccc1)Nc2cc3
2. InChI:InChI=1/C13H9ClN2O/c14-8-5-6-11-12(7-8)16-13(17)9-3-1-2-4-10(9)15-11/p-7,15H,(H,16,17)
3. InChIKey:YVWNDABPZGGQFE-UHFFFAOYAO

99% up 8-Chloro-5,10-Dihydrodibenzo[B,E][1,4]Diazepin-11-One Clozapine Intermediate 50892-62-1

Basic Info

Product Description

Product Information

Product name

8-Chloro-5,10-dihydrodibenzo[b,e][1,4]diazepin-11-one

Clozapine intermediate

CAS No.

50892-62-1

Molecular Formula

C13H9ClN2O

Molecular Weight

244.68

Quality Standard

99% up by HPLC, GMP

Appearance

White powder

Molecular Structure

Synonyms

8-Chloro-5H-dibenzo[b,e][1,4]diazepin-11(10H)-one

Specification

People can use the following data to convert to the molecule structure. 1. SMILES:Clc3cc2NC(=O)c1c(cccc1)Nc2cc3 2. InChI:InChI=1/C13H9ClN2O/c14-8-5-6-11-12(7-8)16-13(17)9-3-1-2-4-10(9)15-11/p-7,15H,(H,16,17) 3. InChIKey:YVWNDABPZGGQFE-UHFFFAOYAO

People can use the following data to convert to the molecule structure.
1. SMILES:Clc3cc2NC(=O)c1c(cccc1)Nc2cc3
2. InChI:InChI=1/C13H9ClN2O/c14-8-5-6-11-12(7-8)16-13(17)9-3-1-2-4-10(9)15-11/p-7,15H,(H,16,17)
3. InChIKey:YVWNDABPZGGQFE-UHFFFAOYAO