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38916-34-6
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98% up by HPLC GMP Somatostatin Acetate 38916-34-6
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Sinoway Industrial Co. Ltd
20
Years
Basic Info
CAS Number
38916-34-6
Pharmacopoeia
In-house Standards
Grade
Pharmaceutical Grade
Is Manufacturer
YES
Packaging & Delivery
Packaging Specification
25kg/drum; 5kg/bag, 1kg/bag
Minimum Order Quantity
1kg
Delivery Cycle
7 days after payment
Product Description
Product Information |
Product name |
Somatostatin acetate |
Alias |
Somatostatina, Somatostatine, Somatostatinum, Somatostatin, cyclic, Somatostatin-14, Aminopan, Panhibin, Somiaton |
CAS No. |
38916-34-6 |
Molecular Formula |
C76H104N18O19S2 |
Molecular Weight |
1637.87 |
Molecule Structure |
|
Quality Standard |
98% up by HPLC, GMP |
Appearance |
White powder |
COA of Somatostatin Acetate |
Items |
Specification |
Results |
Appearance |
White Powder |
Conforms |
Purity(HPLC) |
> 98% |
99.57% |
Specific optical rotation (anhydrous and acetic acid-free substance) |
-37° to -47° |
-41° |
Solubility |
freely soluble in water and in acetic acid, practically insoluble in methylene chloride |
Conforms |
Related substances (HPLC) |
Total impurities: NMT 2.0%
|
1.3%0.3% |
Water (Karl Fischer) |
NMT 8.0 % |
6.5% |
Acetic acid (HPLC) |
3.0% to 15.0 % |
8.7% |
Bacterial endotoxins |
< 10IU/mg |
Conforms |
Assay (anhydrous and acetic acid-free substance) |
95.0% to 104.0% |
99.34% |
Conclusion |
Complies with the standard. |
|
Usage |
Function of Somatostatin Acetate
Somatostatin Acetate is a peptide hormone that regulates the endocrine system and affects neurotransmission and cell proliferation through its interaction with G protein.
① It can inhibit the secretion of growth hormone, thyroid stimulating hormone, insulin and glucagon.
②It can inhibit the secretion of gastric acid stimulated by the test meal and 5-peptide gastrin, and can inhibit the release of pepsin and gastrin.
③It can significantly reduce visceral blood flow, reduce portal vein pressure, reduce blood flow and pressure of collateral circulation, and reduce liver blood flow.
④Reduce the secretion of the pancreas and the secretion of the small intestine and gallbladder, reduce enzyme activity, and have a protective effect on pancreatic cells.
⑤ It can affect the absorption and nutritional function of the gastrointestinal tract.
Application of Somatostatin Acetate
Somatostatin Acetate can be used for severe and acute gastric and duodenal ulcer bleeding; acute erosive or hemorrhagic gastritis severe and acute bleeding; prevention of post-pancreatic complications after pancreatic surgery; inhibition of pancreas and Adjuvant treatment for severe secretion of leaky duct after upper small intestine surgery; regulating human differentiated gastric cancer cell lines
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