*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p><strong>7-Ethyl-Camptothecin</strong> (CAS 78287-27-1) is a potent topoisomerase I inhibitor derived from Camptotheca acuminata. Its molecular formula is C<sub>22</sub>H<sub>20</sub>N<sub>2</sub>O<sub>4</sub>. The compound serves as a critical intermediate in the synthesis of clinical anticancer agents like irinotecan.</p>
<h3>Application</h3>
<ul>
<li>Pharmaceutical R&D for developing novel chemotherapy drugs targeting solid tumors.</li>
<li>Research into DNA replication mechanisms and cell cycle regulation.</li>
<li>Manufacturing process optimization for semi-synthetic camptothecin derivatives.</li>
</ul>
<h3>Precautions</h3>
<p>Strictly store under inert atmosphere at -20°C to prevent lactone ring hydrolysis. Handle with appropriate PPE due to high cytotoxicity; avoid direct contact and inhalation during industrial processing.</p>