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<h3>Overview</h3>
<p><strong>7-chloro-1H-indole-2-carboxylic acid</strong> (CAS: 104985-69-9) is a key heterocyclic intermediate with formula C<sub>9</sub>H<sub>6</sub>ClNO<sub>2</sub>. It is primarily synthesized via chlorination of indole-2-carboxylic acid or Vilsmeier-Haack formylation followed by oxidation.</p>
<h3>Application</h3>
<ul>
<li>Pharmaceutical synthesis as a scaffold for indomethacin analogs.</li>
<li>Agrochemical production for herbicide active ingredients.</li>
<li>Material science for functional organic dyes and pigments.</li>
</ul>
<h3>Precautions</h3>
<p>Store in cool, dry conditions away from oxidizers. Use PPE to prevent skin contact; avoid inhalation of dust. Not for direct clinical use without further derivation.</p>