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Other Specialized Reagents

(6AR,10AR)-7-Methyl-6,6A,8,10A-tetrahydro-4H-indolo[4,3-FG]quinoline-9-carboxylic acid

Category:

Other Specialized Reagents

CAS NO:

5516-88-1

Standard:

In-house Standards,

Price Range:

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Main Sales Markets:

North America,Central/South America,Western Europe,Eastern Europe,Asia

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Capot Chemical Co., Ltd.

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Basic Info

CAS Number

5516-88-1

Pharmacopoeia

In-house Standards

Grade

pharmaceutical grade

Is Manufacturer

YES

Packaging & Delivery

Packaging Specification

1kg、5kg、25kg

Product Description

(6AR,10AR)-7-Methyl-6,6A,8,10A-tetrahydro-4H-indolo[4,3-FG]quinoline-9-carboxylic acid、5516-88-1

AI Product Description

*The following content is generated by AI and is for reference only.

The chemical compound designated as (6AR,10AR)-7-Methyl-6,6A,8,10A-tetrahydro-4H-indolo[4,3-FG]quinoline-9-carboxylic acid is a complex polycyclic organic molecule belonging to the indole-quinoline class. This structure features a fused ring system combining an indole moiety with a quinoline framework, specifically modified with a methyl group at the seventh position and a carboxylic acid functional group at the ninth position. The stereochemistry defined by the (6AR,10AR) configuration indicates specific three-dimensional arrangements critical for its biological interactions, although this precise stereoisomer is primarily utilized in specialized research contexts rather than commercial applications. Currently, there is no widely recognized Commercial Catalog CAS number associated with this exact stereospecific nomenclature in major public databases like PubChem or ChemSpider, suggesting it may be a synthetic intermediate designed for academic investigation or a highly specific derivative within a medicinal chemistry library. Its primary utility lies in the field of pharmaceutical research, particularly in the development of novel kinase inhibitors or DNA intercalating agents. The rigid polycyclic scaffold mimics natural alkaloids, making it a valuable tool for structure-activity relationship (SAR) studies aimed at optimizing drug candidates for oncology or neurodegenerative diseases. Researchers often synthesize such compounds to explore their binding affinity to specific protein targets, leveraging the electron-rich indole and the basic nitrogen of the quinoline rings to form crucial hydrogen bonds and pi-stacking interactions within enzyme active sites. Due to the presence of the carboxylic acid group, this molecule exhibits solubility characteristics suitable for aqueous-based biological assays when converted to salts, while the methyl substituent influences lipophilicity and metabolic stability. While not yet approved for clinical use as a standalone therapeutic agent, derivatives of this core structure contribute significantly to the pipeline of new molecular entities. Scientists utilize this compound to validate hypotheses regarding receptor selectivity and toxicity profiles. Consequently, it serves as an essential building block in high-throughput screening campaigns. For procurement, researchers typically contact custom synthesis laboratories or specialized chemical suppliers who can manufacture this specific stereoisomer upon request, ensuring the required purity and stereochemical integrity for rigorous experimental validation.