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Other Specialized Reagents

6-Bromoimidazo[1,2-a]pyridine

Category:

Other Specialized Reagents

CAS NO:

6188-23-4

Standard:

In-house Standards,

Price Range:

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Main Sales Markets:

North America,Central/South America,Western Europe,Eastern Europe,Asia

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Capot Chemical Co., Ltd.

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Basic Info

CAS Number

6188-23-4

Pharmacopoeia

In-house Standards

Grade

pharmaceutical grade

Is Manufacturer

YES

Packaging & Delivery

Packaging Specification

1kg、5kg、25kg

Product Description

6-Bromoimidazo[1,2-a]pyridine、6188-23-4

AI Product Description

*The following content is generated by AI and is for reference only.

6-Bromoimidazo[1,2-a]pyridine is a versatile heterocyclic building block widely utilized in organic synthesis and medicinal chemistry. With the molecular formula C7H5BrN2 and a CAS registry number of 4983-36-0, this compound features a fused bicyclic structure combining an imidazole ring with a pyridine moiety. The presence of the bromine atom at the six-position renders the molecule highly reactive toward various cross-coupling reactions, making it an indispensable intermediate for constructing complex nitrogen-containing scaffolds. The primary application of 6-Bromoimidazo[1,2-a]pyridine lies in its role as a precursor for pharmaceutical agents and bioactive molecules. Due to the unique electronic properties of the imidazopyridine core, derivatives synthesized from this starting material often exhibit significant biological activities, including antimicrobial, anti-inflammatory, and anticancer properties. Researchers frequently employ palladium-catalyzed cross-coupling methodologies, such as Suzuki-Miyaura, Heck, and Sonogashira reactions, to functionalize the bromo-substituted position. These transformations allow for the introduction of diverse aryl or alkynyl groups, facilitating the rapid generation of library compounds for drug discovery programs. Beyond pharmacology, this heterocycle serves as a valuable ligand in coordination chemistry and materials science. Its ability to coordinate with metal centers makes it useful in designing catalysts and luminescent complexes. Furthermore, the structural rigidity and planarity of the imidazopyridine system contribute to its potential use in developing novel optoelectronic materials. The compound is typically available as a stable, crystalline solid, which simplifies handling and storage in laboratory settings. As the demand for efficient synthetic routes to nitrogen-rich heterocycles grows, 6-Bromoimidazo[1,2-a]pyridine remains a critical reagent for chemists aiming to expand the chemical space of therapeutic candidates and advanced functional materials. Its compatibility with mild reaction conditions and high regioselectivity ensures its continued prominence in both academic research and industrial process development.