*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p><strong>6-Bromo-N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]quinazolin-4-amine</strong> is a high-purity quinazoline derivative synthesized via nucleophilic aromatic substitution. It serves as a critical intermediate in kinase inhibitor development. <strong>Molecular Formula: C21H14BrClFNO2</strong>. <strong>CAS No.: 1379856-05-3</strong>.</p>
<h3>Application</h3>
<ul>
<li>Pharmaceutical R&D for EGFR and HER2 tyrosine kinase inhibitors.</li>
<li>Medicinal chemistry scaffold optimization for oncology drug discovery.</li>
<li>Quality control standard synthesis in active pharmaceutical ingredients (APIs).</li>
</ul>
<h3>Precautions</h3>
<p>Store under inert atmosphere at -20°C to prevent hydrolysis. Use only in licensed laboratories with appropriate PPE due to potential mutagenicity. Not approved for direct clinical use or human consumption.</p>