LEAPChem supplies high quality fine chemicals, intermediates and APIs.
AI Product Description
*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p><strong>5-Chloro-2-fluorophenylboronic acid</strong> (CAS 100489-69-0, C6H5BClFO2) is a key heterocyclic intermediate synthesized via palladium-catalyzed borylation or lithiation-boronation. It serves as a critical building block in cross-coupling reactions for pharmaceutical manufacturing.</p>
<h3>Application</h3>
<ul>
<li>Synthesis of kinase inhibitors and oncology drugs.</li>
<li>Production of agrochemical herbicides and fungicides.</li>
<li>Development of advanced OLED materials and fluorinated ligands.</li>
</ul>
<h3>Precautions</h3>
<p>Store under inert atmosphere at low temperatures to prevent oxidation. Use appropriate PPE against respiratory irritation and skin contact; avoid environmental release due to aquatic toxicity.</p>