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Other Specialized Reagents

4-Chloropyrrolo[2,3-d]pyrimidine

Category:

Other Specialized Reagents

CAS NO:

3680-69-1

Standard:

In-house Standards,

Price Range:

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Main Sales Markets:

North America,Central/South America,Western Europe,Eastern Europe,Asia

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Capot Chemical Co., Ltd.

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Basic Info

CAS Number

3680-69-1

Pharmacopoeia

In-house Standards

Grade

pharmaceutical grade

Is Manufacturer

YES

Packaging & Delivery

Packaging Specification

1kg、5kg、25kg

Product Description

4-Chloropyrrolo[2,3-d]pyrimidine、3680-69-1

AI Product Description

*The following content is generated by AI and is for reference only.

4-Chloropyrrolo[2,3-d]pyrimidine is a versatile heterocyclic building block widely utilized in the fields of medicinal chemistry and organic synthesis. With the molecular formula C6H3ClN4 and a CAS registry number of 1078-95-1, this compound features a fused pyrrole and pyrimidine ring system substituted with a reactive chlorine atom at the fourth position. This specific structural arrangement makes it an essential intermediate for the development of novel pharmaceutical agents, particularly those targeting kinase inhibitors and antiviral therapies. The presence of the chloro group provides a convenient site for nucleophilic substitution reactions, allowing chemists to easily introduce diverse amine or thiol functionalities to generate complex heterocyclic scaffolds. In research and industrial applications, this molecule serves as a foundational precursor for synthesizing purine analogs, which are critical components in the design of anticancer drugs and immunosuppressants. Its high reactivity facilitates efficient coupling reactions under mild conditions, streamlining the synthetic pathways required for drug discovery campaigns. Furthermore, derivatives of 4-chloropyrrolo[2,3-d]pyrimidine have shown promise in modulating biological targets involved in cell signaling and DNA replication processes. Researchers frequently employ this compound to construct libraries of compounds for high-throughput screening assays aimed at identifying potential therapeutic leads. The stability and availability of 4-chloropyrrolo[2,3-d]pyrimidine make it a preferred choice for laboratory-scale synthesis and scale-up production in fine chemical manufacturing. It is typically handled under standard inert atmosphere conditions to prevent premature hydrolysis or degradation, ensuring optimal reaction yields. As the demand for innovative small-molecule therapeutics continues to grow, the role of such heterocyclic intermediaries becomes increasingly significant in accelerating the pipeline from concept to clinical candidate. Consequently, 4-chloropyrrolo[2,3-d]pyrimidine remains a cornerstone material in modern organic chemistry, bridging the gap between simple starting materials and sophisticated bioactive molecules essential for advancing human health.