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<h3>Overview</h3>
<p><strong>4-Chloro-2-ethyl-1-indanone</strong> (CAS: 10397-85-6) is a key intermediate in pharmaceutical synthesis, primarily utilized for manufacturing indomethacin derivatives. The core process involves Friedel-Crafts acylation of chlorobenzene followed by cyclization. Molecular formula: C<sub>10</sub>H<sub>9</sub>ClO.</p>
<h3>Application</h3>
<ul>
<li>Non-steroidal anti-inflammatory drug (NSAID) production as an active pharmaceutical ingredient precursor.</li>
<li>Synthesis of specific heterocyclic compounds for medicinal chemistry research.</li>
<li>Custom chemical manufacturing for bulk API supply chains.</li>
</ul>
<h3>Precautions</h3>
<p>Store in a cool, dry, well-ventilated area away from oxidizers. Use appropriate PPE including gloves and eye protection during handling to prevent skin irritation and inhalation hazards.</p>