Product Description
3-Fluoro-4-hydroxybenzaldehyde、405-05-0
AI Product Description
*The following content is generated by AI and is for reference only.
3-Fluoro-4-hydroxybenzaldehyde is a specialized organic intermediate widely utilized in the fields of medicinal chemistry, agrochemical synthesis, and materials science. With the molecular formula C7H5FO2 and a molecular weight of approximately 140.11 g/mol, this compound features a benzene ring substituted with an aldehyde group at the first position, a hydroxyl group at the fourth position, and a fluorine atom at the third position. Its primary CAS registry number is 364-89-2, which serves as its unique identifier for global chemical databases and regulatory compliance.
The presence of both the phenolic hydroxyl and the formyl groups makes this molecule highly reactive, allowing it to serve as a versatile building block for complex heterocyclic structures. In pharmaceutical research, it is frequently employed in the synthesis of bioactive molecules, including kinase inhibitors, anti-inflammatory agents, and potential antiviral drugs. The fluorine substituent is particularly valuable as it often enhances the metabolic stability, lipophilicity, and binding affinity of drug candidates, thereby improving their overall pharmacological profile. Consequently, 3-fluoro-4-hydroxybenzaldehyde is a critical precursor in the development of novel therapeutics targeting various diseases.
Beyond the pharmaceutical industry, this compound finds applications in the agrochemical sector, where it contributes to the creation of new herbicides and fungicides designed to protect crops more effectively while minimizing environmental impact. Furthermore, researchers utilize it in the synthesis of functional materials, such as luminescent probes and liquid crystals, leveraging its unique electronic properties derived from the electron-withdrawing fluorine atom and the electron-donating hydroxyl group.
Handling this substance requires standard laboratory safety precautions, as it may be irritating to the skin and eyes. It should be stored in a cool, dry place away from incompatible oxidizing agents. Due to its specific reactivity, it is often supplied in high purity grades to ensure consistency in synthetic pathways. As demand grows for more efficient and targeted chemical solutions across multiple industries, 3-fluoro-4-hydroxybenzaldehyde remains an essential component in modern chemical manufacturing and research laboratories worldwide.