*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p><strong>3-amino-5-(trifluoromethoxy)benzonitrile</strong> (CAS: 1267498-47-0) is a specialized fluorinated aromatic intermediate. It is synthesized via nucleophilic substitution of 3-nitro-5-(trifluoromethoxy)benzonitrile followed by catalytic reduction. Molecular formula: C<sub>8</sub>H<sub>5</sub>F<sub>3</sub>N<sub>2</sub>O.</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmaceuticals:</strong> Key scaffold for kinase inhibitors and CNS active agents.</li>
<li><strong>Agricultural Chemicals:</strong> Precursor for novel fungicides and herbicides.</li>
<li><strong>Material Science:</strong> Building block for high-performance liquid crystals.</li>
</ul>
<h3>Precautions</h3>
<p>Store in sealed containers under inert atmosphere at 2-8°C. Avoid skin contact; wear appropriate PPE due to potential toxicity and irritancy. Not approved for direct human consumption or clinical use without further formulation.</p>