Product Description
| Chemical Name: |
2,2,2-Trichloroethyl chloroformate |
| Molecular Formula: |
C3H2Cl4O2 |
| Formula Weight: |
211.86 |
| CAS No.: |
17341-93-4 |
AI Product Description
*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p><strong>2,2,2-Trichloroethyl chloroformate</strong> (CAS: 1548-76-9) is a specialized reagent with molecular formula C<sub>3</sub>H<sub>2</sub>Cl<sub>4</sub>O<sub>2</sub>. It serves as a critical intermediate in organic synthesis, primarily employed for introducing the trichloroethoxycarbonyl (Trt) protecting group during peptide and nucleotide manufacturing processes.</p>
<h3>Application</h3>
<ul>
<li>Synthesis of protected amino acids for pharmaceutical peptides.</li>
<li>Protecting agent in oligonucleotide solid-phase synthesis.</li>
<li>Intermediate production for specific agrochemical active ingredients.</li>
</ul>
<h3>Precautions</h3>
<p>This compound is moisture-sensitive and releases toxic phosgene upon hydrolysis. Strict storage under inert atmosphere at low temperatures is mandatory. Personnel must utilize full PPE including respiratory protection due to severe respiratory irritant properties.</p>