Product Description
2-IODO-6-METHOXYPHENOL、111726-46-6
AI Product Description
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2-Iodo-6-methoxyphenol is a specialized organic compound widely utilized in the fields of medicinal chemistry and materials science. Its molecular formula is C7H7IO2, corresponding to a molar mass of approximately 234.04 g/mol. The substance is identified by the CAS Registry Number 15238-94-7. Structurally, this molecule features a phenolic hydroxyl group at the first position, an iodine atom at the second position, and a methoxy substituent at the sixth position on the benzene ring. This specific substitution pattern creates a unique electronic environment that makes it highly valuable as a versatile building block for complex synthesis.
In pharmaceutical research, 2-iodo-6-methoxyphenol serves as a critical intermediate for constructing biologically active scaffolds. The presence of the carbon-iodine bond allows for efficient cross-coupling reactions, such as Suzuki-Miyaura or Sonogashira couplings, enabling chemists to attach diverse functional groups with high precision. These derivatives are often explored for their potential therapeutic properties, including anti-inflammatory, antimicrobial, or anticancer activities. Furthermore, the iodine atom can be strategically replaced or modified to fine-tune the pharmacokinetic profile of candidate drug molecules.
Beyond medicine, this compound finds applications in the development of advanced materials. It is frequently employed in the synthesis of luminophores and fluorescent probes due to the heavy atom effect of iodine, which can enhance intersystem crossing and phosphorescence. Researchers utilize its structural characteristics to design sensors capable of detecting specific metal ions or biological markers with high sensitivity. Additionally, its reactivity facilitates the creation of novel polymers with tailored optical or electronic properties for use in organic electronics.
Handling 2-iodo-6-methoxyphenol requires standard laboratory safety precautions, as halogenated phenols can be irritating to the skin and eyes. Proper storage in cool, dry conditions away from light is recommended to maintain stability. As demand grows for sophisticated heterocyclic compounds and functionalized aromatics in both academic and industrial settings, 2-iodo-6-methoxyphenol remains an indispensable reagent for advancing chemical innovation and developing next-generation technologies.