Product Description
2-Chlorophenylacetic acid、2444-36-2
AI Product Description
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2-Chlorophenylacetic acid, chemically known as 2-(2-chlorophenyl)acetic acid, is a significant organic compound widely utilized in the pharmaceutical and agrochemical industries. With the molecular formula C8H7ClO2 and a molecular weight of approximately 170.59 g/mol, this white to off-white crystalline powder serves as a crucial intermediate in various synthetic pathways. Its distinctive structure, featuring a chloro-substituted phenyl ring attached to an acetic acid moiety, imparts unique chemical reactivity suitable for diverse applications.
The primary CAS registry number for 2-Chlorophenylacetic acid is 643-04-5, which is essential for accurate identification in global trade and regulatory compliance. In the pharmaceutical sector, this compound acts as a key building block for synthesizing non-steroidal anti-inflammatory drugs (NSAIDs), antihypertensive agents, and other bioactive molecules. The presence of the chlorine atom often enhances the metabolic stability and lipophilicity of the final drug products, thereby improving their therapeutic efficacy. Furthermore, it plays a pivotal role in the production of herbicides and fungicides within the agricultural industry, where it contributes to the development of crop protection chemicals that target specific enzymatic pathways in pests and weeds.
Beyond its industrial utility, 2-Chlorophenylacetic acid is also employed in research laboratories for mechanistic studies regarding electrophilic aromatic substitution and esterification reactions. Chemists frequently utilize it to explore structure-activity relationships (SAR) during drug discovery processes. Handling this substance requires standard safety precautions, including the use of personal protective equipment, as it can be irritating to the skin, eyes, and respiratory tract. Proper storage in cool, dry environments away from incompatible materials such as strong oxidizers is recommended to maintain its purity and prevent degradation.
Overall, 2-Chlorophenylacetic acid remains an indispensable reagent in modern chemistry. Its versatility in facilitating complex molecular architectures underscores its value across multiple scientific disciplines. As demand for advanced pharmaceuticals and sustainable agricultural solutions grows, the strategic importance of this versatile intermediate continues to expand, driving innovation in synthesis methodologies and product development globally. Researchers and manufacturers rely on its consistent quality to ensure the successful scale-up of new chemical entities from the laboratory bench to commercial production.