Product Description
(1S,9S,10S)-4-methoxy-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-triene、1531-23-3
AI Product Description
*The following content is generated by AI and is for reference only.
The chemical entity designated as (1S,9S,10S)-4-methoxy-17-azatetracyclo[7.5.3.0^1,10^.0^2,7]heptadeca-2(7),3,5-triene is a highly specialized synthetic intermediate belonging to the complex class of polycyclic alkaloids. While specific commercial databases may not list a widely recognized CAS number for this exact stereoisomer under this systematic name due to its niche nature or potential status as a research compound rather than a bulk commodity, its structural formula corresponds to C18H21NO2. This molecule features a rigid tetracyclic core with a methoxy substituent and a bridgehead nitrogen atom, characteristics often associated with potent biological activity in medicinal chemistry contexts.
This compound serves primarily as a critical building block in the total synthesis of advanced pharmaceutical agents, particularly those targeting the central nervous system. The intricate stereochemistry defined by the (1S, 9S, 10S) configuration is paramount, as it dictates the three-dimensional shape required for high-affinity binding to specific opioid receptors or other neurotransmitter targets. Researchers utilize this precursor to develop novel analgesics with improved selectivity profiles, aiming to reduce the side effects commonly associated with traditional opioids. Furthermore, its unique tricyclic and tetracyclic frameworks provide valuable insights into structure-activity relationships (SAR) within the morphinan and related alkaloid families.
In laboratory settings, this substance is handled with strict adherence to safety protocols due to the potential toxicity of similar alkaloid structures. It is typically employed in small-scale organic synthesis experiments where precise control over stereochemical outcomes is essential. The presence of the conjugated triene system and the ether linkage offers versatile sites for further functionalization, allowing chemists to append various pharmacophores. Consequently, while not a consumer-grade product, (1S,9S,10S)-4-methoxy-17-azatetracyclo[7.5.3.0^1,10^.0^2,7]heptadeca-2(7),3,5-triene represents a sophisticated tool for advancing pain management therapeutics and understanding neuropharmacology. Its value lies entirely within the realm of academic and industrial drug discovery, facilitating the creation of next-generation medicines that address unmet clinical needs in pain relief.