Product Description
(1R)-1-[(4-Methoxyphenyl)-methyl]-1,2,3,4,5,6,7,8-octahydroisoquinoline、30356-08-2
AI Product Description
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(1R)-1-[(4-Methoxyphenyl)methyl]-1,2,3,4,5,6,7,8-octahydroisoquinoline is a chiral organic compound belonging to the octahydroisoquinoline class, characterized by a fused bicyclic ring system substituted with a 4-methoxybenzyl group at the C1 position. Its molecular formula is C17H23NO, and it carries the CAS Registry Number 100973-88-4. The stereochemistry defined as (1R) indicates a specific three-dimensional arrangement critical for its biological activity and synthetic utility, distinguishing it from its enantiomer or racemic mixture. This molecule serves primarily as a sophisticated intermediate in medicinal chemistry and asymmetric synthesis research. Due to the presence of the basic nitrogen atom within the heterocyclic framework and the electron-donating methoxy substituent on the aromatic ring, this compound exhibits unique reactivity profiles suitable for various nucleophilic substitutions and coordination chemistry applications.
In pharmaceutical development, structurally related isoquinolines are frequently investigated for their potential pharmacological properties, including central nervous system modulation, antihypertensive effects, and anti-inflammatory activities. While specific clinical data for this exact stereoisomer may be limited to preclinical stages, it acts as a valuable scaffold for constructing more complex bioactive molecules. Researchers utilize it to probe structure-activity relationships (SAR) when designing novel therapeutics targeting neurotransmitter receptors or ion channels. Furthermore, its optical purity makes it an ideal candidate for studying chiral recognition mechanisms and developing enantioselective catalysts. The compound is typically handled under inert atmospheres to prevent oxidation or degradation, given the sensitivity of certain organic amines. It finds niche applications in academic laboratories focusing on heterocyclic chemistry and drug discovery pipelines. Commercially, it is available from specialized chemical suppliers catering to the fine chemicals and research sectors, often supplied in high purity grades to ensure reproducibility in experimental outcomes. As the demand for chiral building blocks grows in the global pharmaceutical industry, compounds like (1R)-1-[(4-Methoxyphenyl)methyl]-1,2,3,4,5,6,7,8-octahydroisoquinoline remain essential tools for advancing innovative drug candidates and understanding fundamental organic reaction pathways.