Melting point - 4 ° C (lit.)
Boiling point 59 ° C (lit.)
The density of 1.615 g/mL at 25 ° C
Index of refraction n20/D 1.275(lit.)
Flash point 59 ° C
Storage conditions Store below 30 ° C +.
Liquid form
The proportion of 1.6
Color Clear colorless
PH 3-4 (H2O) Aqueous solution
The water solubility is Fully miscible in water.
Moisture Sensitive
*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p><strong>1,1,1,3,3,3-Hexafluoro[2-2H]propan-2-[2H]ol</strong> (CAS 38701-74-5) is a deuterated fluorinated solvent used primarily in NMR spectroscopy. Its synthesis involves isotopic exchange or specific deuteration of hexafluoroisopropanol.</p>
<h3>Application</h3>
<ul>
<li><strong>NMR Solvent:</strong> Provides a deuterium lock signal for proton and carbon analysis without interfering peaks.</li>
<li><strong>Spectroscopic Standard:</strong> Used as an internal reference for precise chemical shift calibration.</li>
<li><strong>Research:</strong> Essential for studying metabolic pathways and reaction mechanisms involving hydrogen-deuterium exchange.</li>
</ul>
<h3>Precautions</h3>
<p>Store in tightly sealed containers away from moisture to prevent hydrolysis. Use only in well-ventilated areas with appropriate PPE due to potential respiratory irritation. Not intended for clinical drug administration.</p>