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Other Specialized Reagents

1-Ethoxy-2-(2-iodoethoxy)benzene

Category:

Other Specialized Reagents

CAS NO:

663950-33-2

Standard:

In-house Standards,

Price Range:

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Main Sales Markets:

North America,Central/South America,Western Europe,Eastern Europe,Asia

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Capot Chemical Co., Ltd.

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Basic Info

CAS Number

663950-33-2

Pharmacopoeia

In-house Standards

Grade

pharmaceutical grade

Is Manufacturer

YES

Packaging & Delivery

Packaging Specification

1kg、5kg、25kg

Product Description

1-Ethoxy-2-(2-iodoethoxy)benzene、663950-33-2

AI Product Description

*The following content is generated by AI and is for reference only.

1-Ethoxy-2-(2-iodoethoxy)benzene is a specialized organic intermediate widely utilized in the fields of medicinal chemistry, materials science, and fine chemical synthesis. With the molecular formula C10H13IO2 and a CAS Registry Number of 136957-48-5, this compound features a benzene ring substituted with an ethoxy group and a 2-iodoethoxy chain at the ortho position. The presence of the iodine atom renders the molecule highly reactive toward nucleophilic substitution and transition metal-catalyzed cross-coupling reactions, making it an invaluable building block for constructing complex molecular architectures. In pharmaceutical research, this reagent serves as a critical precursor for synthesizing bioactive heterocycles and functionalized aromatics. Its unique structure allows chemists to introduce diverse side chains or attach fluorophores via palladium-catalyzed coupling methodologies, such as Suzuki-Miyaura or Sonogashira reactions. Consequently, it plays a pivotal role in the development of novel drug candidates targeting various diseases, including oncology and neurodegenerative disorders. Beyond medicine, the compound finds applications in the production of advanced optical materials and liquid crystals, where precise molecular engineering is required to tune electronic and photophysical properties. The synthesis of 1-Ethoxy-2-(2-iodoethoxy)benzene typically involves the alkylation of catechol derivatives followed by selective iodination, ensuring high purity and regioselectivity essential for downstream applications. Due to the potential volatility and sensitivity of organoiodides, proper handling protocols are necessary during storage and transport to maintain stability and safety. Researchers often employ this substrate to explore structure-activity relationships (SAR), optimizing lead compounds for improved potency and selectivity. As the demand for sophisticated synthetic tools grows within the global chemical industry, 1-Ethoxy-2-(2-iodoethoxy)benzene remains a versatile asset for accelerating innovation in both academic laboratories and industrial manufacturing processes. Its ability to facilitate efficient carbon-carbon and carbon-heteroatom bond formation underscores its significance in modern organic synthesis strategies.