1-(4-Iodophenyl)-2-piperidinone
- Cas No:385425-15-0
- Purity:98%+
- Molecular Formula:C11H12INO
- Molecular Weight:301.12
- EINECS No.:N/A
- Melting point:N/A
- Boiling point:N/A
- Hazard Class:Non-dangerous
- H.S. Code:29420000
- Usage:Apixaban Intermediates
- Package:25kg/drum or on customer request
- Storage condition:Room temperature.
- Appearance:Colorless crystal
*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p><strong>1-(4-Iodophenyl)-2-piperidinone</strong> is a specialized iodinated heterocyclic intermediate used in pharmaceutical synthesis. Its core production involves the coupling of piperidinone derivatives with 4-iodoaryl reagents under controlled catalytic conditions. The molecular formula is C<sub>11</sub>H<sub>12</sub>INO and CAS No. is 875936-88-0.</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmaceutical R&D:</strong> Serves as a key building block for radioligand development in PET imaging studies.</li>
<li><strong>Medicinal Chemistry:</strong> Utilized in constructing complex kinase inhibitors and CNS-active drug candidates.</li>
<li><strong>Material Science:</strong> Applied in synthesizing functionalized polymers with specific radio-opacity properties.</li>
</ul>
<h3>Precautions</h3>
<p>Store strictly under inert atmosphere at -20°C to prevent hydrolysis. Personnel must wear appropriate PPE including nitrile gloves and safety goggles due to potential skin irritation and light sensitivity of the iodine moiety. Avoid inhalation of dust particles during handling.</p>