*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p><strong>1-(4-Fluorophenyl)piperazine</strong> (CAS: 360-29-0) is a key heterocyclic intermediate with formula C<sub>11</sub>H<sub>13</sub>FN. Synthesized via nucleophilic substitution of piperazine and 1-fluoro-4-bromobenzene, it serves as a critical building block in pharmaceutical manufacturing.</p>
<h3>Application</h3>
<ul>
<li>Synthesis of antipsychotic agents like fluphenazine derivatives.</li>
<li>Production of selective serotonin receptor modulators.</li>
<li>Development of novel CNS active compounds.</li>
</ul>
<h3>Precautions</h3>
<p>Store in cool, dry place away from oxidizers. Use appropriate PPE to avoid skin contact; inhalation may cause respiratory irritation. Strictly adhere to GMP guidelines for API production.</p>