Product Description
1-(10-aza-tricyclo[6.3.1.02,7]dodeca-2(7),3,5-trien-10-yl)-2,2,2-trifluoro-ethanone、230615-51-7
AI Product Description
*The following content is generated by AI and is for reference only.
1-(10-aza-tricyclo[6.3.1.0²,⁷]dodeca-2(7),3,5-trien-10-yl)-2,2,2-trifluoroethanone is a specialized organic compound characterized by a unique tricyclic framework fused with a trifluoromethyl ketone moiety. Its molecular formula is C₁₂H₉F₃NO, reflecting a structure that combines the rigid geometry of a bridged azabicyclic system with the strong electron-withdrawing properties of the trifluoroacetyl group. While specific commercial Cas numbers for this exact stereoisomer may vary depending on synthesis routes or supplier cataloging, it generally falls within the domain of advanced synthetic intermediates used in medicinal chemistry and materials science research. The core scaffold, derived from 10-azatricyclo[6.3.1.0²,⁷]dodeca-2(7),3,5-triene, offers significant steric constraints and electronic modulation, making it highly valuable for exploring novel pharmacophores.
The trifluoromethyl ketone functionality serves as a critical reactive handle, facilitating nucleophilic additions, reductive aminations, and other transformations essential for building complex molecular architectures. In pharmaceutical development, such compounds are often investigated for their potential to modulate biological targets, particularly where metabolic stability and lipophilicity are paramount. The introduction of fluorine atoms enhances membrane permeability and can improve binding affinity through electrostatic interactions with protein residues. Consequently, this molecule finds application in the synthesis of heterocyclic drugs, agrochemicals, and functional materials requiring precise structural tuning. Researchers utilize it as a key building block to construct libraries of analogs for high-throughput screening assays. Despite its niche status, the compound represents an important intersection of structural complexity and chemical reactivity. It allows chemists to probe structure-activity relationships (SAR) with high precision, leveraging the unique three-dimensional shape of the tricyclic amine. As demand grows for novel therapeutics targeting resistant pathogens or difficult-to-drug proteins, derivatives like this one will likely play an increasingly vital role in modern drug discovery pipelines, offering a versatile platform for generating diverse bioactive molecules with optimized physicochemical profiles.