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Other Specialized Reagents

(-)-Menthyl Chloroformate

Category:

Other Specialized Reagents

CAS NO:

14602-86-9

Standard:

In-house Standards,

Price Range:

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Main Sales Markets:

North America,Central/South America,Western Europe,Eastern Europe,Asia

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Capot Chemical Co., Ltd.

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Basic Info

CAS Number

14602-86-9

Pharmacopoeia

In-house Standards

Grade

pharmaceutical grade

Is Manufacturer

YES

Packaging & Delivery

Packaging Specification

1kg、5kg、25kg

Product Description

(-)-Menthyl Chloroformate、14602-86-9

AI Product Description

*The following content is generated by AI and is for reference only.

(-)-Menthyl Chloroformate is a specialized chiral reagent widely utilized in organic synthesis and pharmaceutical development. With the molecular formula C11H19ClO2, this compound serves as a crucial intermediate for introducing menthyl groups into various molecular structures. Its primary Chemical Abstracts Service (CAS) registry number is 7645-30-1, which facilitates precise identification and procurement across global chemical markets. The molecule consists of a chloroformate functional group attached to a (-)-menthol backbone, providing distinct stereochemical properties essential for asymmetric synthesis. The principal application of (-)-Menthyl Chloroformate lies in its role as a chiral auxiliary and protecting group agent. Chemists frequently employ it to convert alcohols, amines, or acids into their corresponding carbamates or esters with high stereoselectivity. This capability is particularly valuable in the synthesis of complex natural products, bioactive compounds, and novel drug candidates where enantiomeric purity is paramount. By utilizing this reagent, researchers can effectively distinguish between enantiomers during purification processes or utilize the resulting derivatives to induce chirality in subsequent reaction steps. Furthermore, it acts as an efficient coupling agent in peptide chemistry, helping to minimize racemization during amide bond formation. Due to its reactive nature, proper handling requires adherence to strict safety protocols. As an acid chloride derivative, it reacts vigorously with water, releasing hydrogen chloride gas; therefore, storage must occur under anhydrous conditions at low temperatures. It is typically handled within inert atmospheres such as nitrogen or argon to prevent premature decomposition. In industrial settings, it is used on a smaller scale compared to bulk chemicals, primarily serving research laboratories and specialty chemical manufacturers focused on high-value fine chemicals. The demand for (-)-Menthyl Chloroformate continues to grow alongside advancements in chiral catalysis and the increasing need for pure enantiomers in the pharmaceutical industry. Its unique combination of reactivity and stereochemical control makes it an indispensable tool for modern synthetic chemists aiming to construct complex molecular architectures with precision.