A recent journal related defined digital biomarkers as objective and measurable physiological and behavioral data. These are collected using digital devices like wearable's, portable's, implantable's, or ingestible's. This data helps explain, influence, and even predict health outcomes. Digital biomarkers offer a promising way to capture clinically relevant, objective data about a person's health. This field is inherently multidisciplinary, bringing together computer science, engineering, biomedicine, regulatory science, and informatics.[1]
The 2023 COMPAMED Innovation Forum in Düsseldorf, Germany, showcased how leading international experts are integrating modern sensor technology into medical devices for diagnosis and treatment. Some of the innovation products are discussed below from the leading international sensor based companies.[2]
New sensor-based devices are transforming how we collect and use clinical data, impacting decision-making. Companies like ES Systems develop compact sensors for medical devices (e.g., nebulizers) and monitor patient vitals (e.g., blood pressure). They're also using sensors and IoT to tackle Hospital Acquired Infections (HAIs). Traditional methods rely on manual checks, which can miss outbreaks. Sensors provide real-time data and trigger automated alerts for potential risks (e.g., temperature spikes). This allows for faster intervention and infection prevention. Pilot studies show promise in reducing HAIs, a significant cause of death in hospitals.[3]
Piezoelectric technology using ultrasound sensors enhances medical devices like infusion systems. These sensors help monitor vital signs and improve patient safety. A key application is air bubble detection in infusion systems. Air bubbles can be deadly, so immediate detection is crucial. Piezo sensors measure sound waves to detect bubbles based on how they reflect. This allows for real-time monitoring and immediate interruption if an air bubble is found. An advantage of piezo sensors is their compact size and non-invasive nature.They can be attached externally to tubes, preventing contamination of fluids.[4]
Epicore Biosystems, US-based a biomedical device/ biosensors based biotech company that offers wearable microfluidic patches to analyze sweat for non-invasive health monitoring. Founded in 2017, they've partnered with major companies and research institutions. Their key products are 1) Discovery Patch System: This wearable patch collects sweat for lab analysis in clinical trials and research, 2) Gx Sweat Patch (with Gatorade): This patch tracks sweat biomarkers to provide personalized hydration and performance recommendations for athletes; & 3) Connected Hydration: This wearable tracker continuously monitors sweat loss, electrolytes, and body temperature to offer personalized hydration plans with dehydration alerts. These products are beneficial since these are non-invasive sweat analysis for various health applications, personalized hydration recommendations for athletes & streamlined sweat collection for research purposes. The multidisciplinary use of technologies include microfluidic patches capture sweat from the skin, sensors measure sweat volume, electrolytes, and body temperature, also algorithms that analyze data to provide personalized insights.[5]
SmartNanotubes Technologies, partnering with duotec GmbH, has created a groundbreaking gas detector nano-chip for widespread use. This tiny chip is packed with high-performance features: Highly sensitive thanks to its specially designed nanomaterial. Energy-efficient for long-lasting operation. Compact for easy integration into various devices. Affordable for mass production. The sensor can detect a wide range of gases and volatile organic compounds (VOCs). This versatility makes it suitable for numerous applications, including: Environmental and security monitoring, home and industrial safety systems, wearable health trackers and other IoT devices.[6]
Photonics, the science of light, is being used to develop innovative biosensors for disease detection. A new white paper highlights a collaboration between PHIX and Surfix Diagnostics on a photonic biosensor for early cancer d...
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