According to data of EvaluatePharma, the top 2 on the following list are Kite Pharma’s CAR-T therapy and Incyte’s IDO inhibitor, and DBV’s peanut allergy vaccine and Karyopharm’s cancer treatment selinexor also rank in the top 15. While the potential of the two drugs of Kite and Incyte is generally recognized, opinions on other products on the list are likely to be divided.

Equity analysts are not typically known for their prudence when evaluating the R&D work of small drug development companies, therefore, the values (net present value figures) forecast are far less important than the fact that those drugs rank among the following list. In addition, the drugs in development listed in the following list are limited only to the assets owned in major European countries and U.S. companies.
|
Drug |
Company |
Today’s NPV (USD 100 million) |
NPV as % of market value |
Pharmaceutical product type |
Main indication |
R&D phase |
|
Axicabtagene ciloleucel |
Kite Pharma |
78.1 |
111% |
Anti-CD19 CAR-T |
Non-Hodgkin lymphoma |
Filed application |
|
Epacadostat |
Incyte |
59.8 |
23% |
IDO-1 inhibitor |
Melanoma |
Phase III |
|
AndexXa |
Portola Pharmaceuticals |
28.8 |
91% |
Factor Xa inhibitor antidote |
Factor Xa inhibitor reversal agent |
Filed application |
|
Viaskin Peanut |
DBV Technologies |
28.6 |
152% |
Peanut allergy vaccine |
Peanut allergy |
Phase III |
|
Intepirdine |
Axovant Sciences |
26.4 |
97% |
5-HT6 antagonist |
Alzheimer's disease |
Phase III |
|
AVXS-101 |
Avexis |
24.8 |
84% |
Gene therapy |
Spinal muscular atrophy (SMA) |
Pha... Read More
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