1. What is Spinosad powder?
Spinosad is a naturally occurring substance. It is produced by a soil bacterium. Spinosad is toxic to insects and is a mixture of two compounds; spinosyn A and spinosyn D. It is widely available in the market as a powder that can be used to control pests like mosquitoes, ants, fruit flies, and others. This chemical was first registered in 1997 by the US Environmental Protection Agency (EPA) to be used for this purpose.
Definition
Spinosad is a group of compounds from the spinosyn family that has a unique tetracyclic ring system attached to a neutral and amino sugar.
Chemical & Physical Features
IUPAC name: (1S,2R,5S,7R,9R,10S,14R,19S)-15-[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy-19-ethyl-14-methyl-7-[(2R,3R,4R,5S,6S)-3,4,5-trimethoxy-6-methyloxan-2-yl]oxy-20-oxatetracyclo[10.10.0.02,10.05,9]docosa-3,11-diene-13,21-dione
Synonyms: Spinosyn-A, CHEMBL1874717, NCGC00163954-01, NCGC00163954-02
CAS: 168316-95-8 (A), 131929-60-7 (D)
Molecular formula: C41H65NO10
Molecular weight: 732.0
Form: crystalline solid powder
Color: colorless or cream-colored
Solubility: not easily soluble in water
Brand names
Comfortis
Trifexis
Natroba
2. Spinosad powder Forms and Specifications
You can easily find the Spinosad in multiple forms and specifications in the market, depending on its use. Here are some of the common forms it is available:
Spinosad API powder 97%
The Spinosad API powder is available in the market easily. It is sourced commonly from China or India. Its common uses include as active pharma ingredients for pesticides or insecticides. Spinosad powder is available in 97 percent purity.
Spinosad spray
Spinosad spray is used as an organic pesticide for crops. This spray can help kill foliage-eating worms, fire ants, pests, thrips, and others. Spinosad spray helps with controlling insects in lawns, outdoor ornamental plants, and trees.
Spinosad topical suspension
Spinosad topical suspension can be used for multiple pharmaceutical purposes. It can be used to treat pets that have some infestations like pests or flies. It also has human applications as it can be used to kill lice.
Spinosad concentrate
Spinosad concentrate is used to formulate the other types of Spinosad forms and specifications. It is formed by Spinosad powder on an industrial scale. Spinosad concentrate can then be used as an insecticide by mixing it in water. After mixing, it is typically applied on both the upper and lower sides of plant foliage.
3. Mechanism of Action of Spinosad powder
Spinosad powder works by affecting the nervous system of insects it kills. The insects get affected when they eat or touch this powder. The powder causes the muscles of insects to flex uncontrollably. This then leads to paralysis and eventual death within a day or two.
4. Spinosad powder Manufacturing Process
The manufacturing process of Spinosad begins with the fermentation of a strain of Saccharo-polyspora spinosa. This is followed by extraction of the mixture from the fermentation broth that contains both spinosyn A and D. the mixture is then dried and converted into a powdered form which is light grey or white.
5. Spinosad powder Benefits
There are many uses for Spinosad powder. Some of them include:
Pesticide
Spinosad can act as a pesticide. It is a naturally occurring insecticide that has widespread application as an insect killer.
Spinosad for Cats
Pets such as cats often get inflicted with fleas. An easy way to get rid of these fleas is giving cats medication containing Spinosad, which is FDA approved and can help get rid of such infestations.
Spinosad for Dogs
Spinosad for dogs can be used to kill and prevent flea infestations as well.
6. Spinosad powder Side Effects
Like all chemical substances, Spinosad powder can have side effects. Some of the side effects for humans can be:
Eye irritation
Redness in eyes
Redness or irritation at the application site
7. Spinosad powder Price
The price of Spinosad powder varies by region and its quality. However, the average price of the Spinosad powder from China is between 50-200 USD per kg.
8. Spinosad powder Manufacturers in China
With the increase of information sources, it can become difficult to understand all the supply chains available for the APIs needed for business. If you are looking for quality Spinosad powder API, a user-friendly source is pharmasources.com. The website lists prominent and top manufacturers for a range of pharmaceutical APIs, along with brief company profiles.
Here are some of the leading Spinosad powder manufacturers in China:
Zhejiang Hisun Pharma. Co., Ltd.
The company is one of the leading producers of Drug products, API products, and Research and Development. They are suppliers of top-class Spinosad powder API all around the world. Not only this, the APIs are generally available at wholesale rates.
BrightGene Bio-Medical Technology Co., Ltd.
BrightGene Bio-Medical Technology is in the business of research, manufacturing, and development of biopharmaceuticals such as antifungal drugs, iron supplements agents, cardiovascular drugs, and APIs like Spinosad powder. The company supplies these products and materials all over the world from China.
AVF Chemical Industrial Co., Ltd.
AVF Chemical Industrial corporation is a specialized company based in Shandong China. It manufactures and produces pharmaceutical APIs. The company is well respected in its field and is known for its top-quality material.
Beijing Global Biologicals Co., Ltd
Beijing Global Biologics was established in 2004 and is a leading supplier of active pharmaceutical ingredients around the world including Spinosad powder. It manufactures biological products out of China.
FUZHOU CONTAY BIOTECHNOLOGY CO., LTD.
Founded in 2015, the company is a manufacturer and distributor of biological compounds at economical and wholesale rates. It is known for supplying pure Spinosad powder and concentrate to pharmaceutical companies.
9. FAQs
What does Spinosad kill?
Spinosad can kill a variety of insects and pests. It can kill anything ranging from crop termites to house pests like flies and mosquitoes.
Is Spinosad toxic to humans?
Yes, Spinosad can be toxic to humans and other mammals. It can cause low toxicity when eaten, but if your skin or eye gets exposed it can cause mild irritation and redness.
What's the market size for Spinosad?
Market size for Spinosad is likely to increase according to studies conducted on the topic. A recent report estimated that the global Spinosad market exceeded 275 million USD in 2020.
References
http://npic.orst.edu/factsheets/spinosadgen.html
https://pubchem.ncbi.nlm.nih.gov/compound/Spinosad#section=Names-and-Identifiers
https://en.wikipedia.org/wiki/Spinosad
https://www.drdarrinlew.us/insect-control/production-of-spinosad.html
https://www.reportlinker.com/p03971316/Spinosad-Global-Product-Intelligence.html
https://www.comfortis.com/about-comfortis
https://www.rxlist.com/consumer_spinosad_natroba/drugs-condition.htm
http://www.hisunusa.com
https://www.bloomberg.com/profile/company/1467660D:CH
http://www.avfchem.com
https://www.pharmasources.com/company-home/beijing-global-biologicals-co-ltd-userId-16831.html
(All Rights Reserved)