sanguinarine use.
This is a quaternary benzophenanthridine alkaloidextracted from some plants, including Bloodroot (Sanguinaria canadensis), Mexican Prickly Poppy (Argemone mexicana), Chelidonium majus, and Macleaya cordata and is used in some oral healthcare products. Sanguinarine is a potent suppressor of NF-β activation and induces a rapid apoptotic response by glutathione-depletion.










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