Freeman Technology News - Getting to grips with granulation: a new eBook from Freeman Technology
An in-depth assessment of the application and value of powder flow testing in the optimisation of granulation processes.
May 28, 2021
by Tim Freeman
Quantifying Caking using the FT4 Powder Rheometer®
Many materials in the food, chemical and pharmaceutical industries, from raw materials, additives and intermediates through to manufactured products, are supplied as relatively free-flowing powders suitable for the manufacturing process or final applicati
March 26, 2021
by Tim Freeman
Using Powder Testing to Optimise the Processing Characteristics of Amorphous Solid Dispersions
The use of amorphous solid dispersions (ASDs), in which the active(s) is dispersed in a hydrophilic, water soluble excipient or matrix, is a widely recognised strategy for enhancing the bioavailability of poorly soluble drugs.
January 18, 2021
by Tim Freeman
Limitations of Simple Powder Flow Measurements and Particle Size Analysis for Bulk Powder Characterisation
An important point to appreciate about powders is that they are essentially three-phase systems consisting of solid particles, liquid (often relatively poorly controlled levels of water) and gas, typically air.
November 18, 2020
by Tim Freeman
Powder Flow:Predicting Flow Performance in Screw Feeders
In powder handling industries, screw feeders are routinely used to control the flow of material from a hopper into the subsequent stage of a process.
October 21, 2020
by Tim Freeman
Freeman Technology News - New eBook from Freeman Technology addresses the critical issue of powder flow testing for Additive Manufacturing
Providing expert guidance on relevant techniques and the value of the resulting data.
October 21, 2020
by Tim Freeman
Powder Flow:Developing a Design Space for OTC Manufacturing
Tim Freeman, Managing Director at Freeman Technology, explains how comprehensive, process relevant characterization of wet granules can lead to control of tablet CQAs and assist Design Space definition in the manufacture of an OTC medicine.
October 21, 2020
by Tim Freeman
Powder Flow:Understanding the Impact of High-Shear Blending
In many industries, powders are combined with other powders, or binders, in high-shear blending operations, forming homogeneous mixtures for further downstream processing.
October 21, 2020
by Tim Freeman
Powder Flow: Limitations of Mathematically Derived Parameters from Shear Cell Testing
Shear Cell testing was originally designed to determine the incipient flow of continuous, cohesive powders under applied stress in order to simulate flow from a hopper/silo.
August 3, 2020
by Tim Freeman
Powder Flow: Optimising Unit Operations using the FT4 Powder Rheometer®
Powder Flow: Manufacturing Support using the FT4 Powder Rheometer®
June 24, 2020
by Tim Freeman
WEBINAR: POWDER FLOW ENHANCEMENT IN BATCH AND CONTINUOUS PROCESSES
Poor flow can lead to processing problems, e.g. inconsistent feeding, air entrainment, but more importantly also to rejections due to compromised dosage uniformity. Active Pharmaceutical Ingredients (APIs) in particular often exhibit poor flowability.
June 17, 2020
by Tim Freeman
Powder Flow: Manufacturing Support using the FT4 Powder Rheometer®
By investing in powder rheology, manufacturing sites can establish an understanding of their processes and unit operations based on a correlation between measurable powder properties and process performance.
May 24, 2020
by Tim Freeman