Dr.Ron's Insights: Statistics Roundtable-Raise Your Batting Average(3)
The SCO strategy has stood the test of time, and it’s definitely worth your consideration.
November 27, 2017
by Ronald D. Snee, PhD
Dr.Ron's Insights: Statistics Roundtable-Raise Your Batting Average(2)
Over the years, it has been recognized that experimentation is more effective when it is approached with a strategy in mind.
October 30, 2017
by Ronald D. Snee, PhD
Dr.Ron's Insights: Statistics Roundtable-Raise Your Batting Average(1)
Remember the importance of sequence in experimentation
October 10, 2017
by Ronald D. Snee, PhD
Dr.Ron's Insight: Robust Experimental Strategies for Improving Upstream Productivity (3)
Another problem that can reduce the speed and quality of process development is themeasurement systems used to collect the data, i.e, availability of good methods and the efficiency with which the analytical laboratory is operated.
August 28, 2017
by Ronald D. Snee, PhD
Dr.Ron's Insight: Robust Experimental Strategies for Improving Upstream Productivity (2)
Critical to success is the development of a strategy of experimentation, which streamlines the experimental process. Such a strategy, summarized in Table I, identifies three experimental environments: screening, characterization, and optimization.
July 31, 2017
by Ronald D. Snee, PhD
Dr.Ron's Insight: Robust Experimental Strategies for Improving Upstream Productivity (1)
Experience using Quality by Design in upstream processes has identified several things that can improve the application of the method.
June 26, 2017
by Ronald D. Snee, PhD
Quality by Design -- Experimental strategies for implementing Quality by Design (2)
Critical Elements ofExperimental Strategies for Implementing QbD Process and product Xs and Ys: TheYs - Critical Quality Attributes (CQAs) are the critical process output measurements linked to patient needs.
May 27, 2017
by Ronald D. Snee, PhD
Quality by Design -- Experimental strategies for implementing Quality by Design
Much has been learned about the use of Quality by Design (QbD) since it was proposed by the FDA and ICH (2005) some five years ago. While the benefits of the approach are generally acknowledged, its implementation has been slower than expected.
April 25, 2017
by Ronald D. Snee, PhD
Think Strategically for Design of Experiments Success (3)
Administration of an experimental program is a vital step that is often overlooked. It must be carefully planned and executed. As John Wooden, arguably the most successful college basketball coach ever, has admonished us, “Failing to plan is planning to f
March 27, 2017
by Ronald D. Snee, PhD
Think Strategically for Design of Experiments Success (2)
It should not be overlooked that DoE can be used to improrove the repeatability, reproducibility, and robustness of analytical methods.
February 23, 2017
by Ronald D. Snee, PhD
Think Strategically for Design of Experiments Success (1)
QualityGlobal competition fueled by the power of information technology has forced the pharmaceutical and biotechnology industries to seek new ways to compete.
January 17, 2017
by Ronald D. Snee, PhD